Abstract:
Mild cognitive impairment( MCI) is the transition state between normal aging and AD. There are better detection and treatment methods to screen a population of patients with MCI. Through intervention, the probability of MCI conversion to AD can be significantly reduced. This paper first introduces the concept of cost-effectiveness analysis,reconsiders the concept of cost for the particularity of MCI, and uses QALY to evaluate the health effects of the quality of life. Then measure the health quality of life of elderly MCI population, and use Markov model to study the cost of intervention with traditional Chinese medicine-effectiveness analysis. Finally, according to the QALY measure and CEA results,we draw the conclusion that it's helpful to get early intervention in MCI.
Key words:
Mild cognitive impairment; Traditional Chinese medicine intervention; Cost-effectiveness analysis; Quality-adjusted
Fund:
the National Science & Technology Major Project of China “Key NewDrug Creation and Manufacturing Program” (2009ZX09502-030); Beijing's major project “New Medical Discipline Group” (XK100270569);
Reference:
Wang, N., Zhang, Z., & Chang, D. (2012). Using Markov model to cost-effectiveness analysis of traditional Chinese medicine interference. China Journal of Chinese Materia Medica, 37(18), pp.2698-2701. (《运用Markov 模型对中药干预的成本-效果分析》)
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